Spatial clustering of mental disorders and associated characteristics of the neighbourhood context in Malmö, Sweden, in 2001

Study objective: Previous research provides preliminary evidence of spatial variations of mental disorders and associations between neighbourhood social context and mental health. This study expands past literature by (1) using spatial techniques, rather than multilevel models, to compare the spatial distributions of two groups of mental disorders (that is, disorders due to psychoactive substance use, and neurotic, stress related, and somatoform disorders); and (2) investigating the independent impact of contextual deprivation and neighbourhood social disorganisation on mental health, while assessing both the magnitude and the spatial scale of these effects. Design: Using different spatial techniques, the study investigated mental disorders due to psychoactive substance use, and neurotic disorders. Participants: All 89 285 persons aged 40–69 years residing in Malmö, Sweden, in 2001, geolocated to their place of residence. Main results: The spatial scan statistic identified a large cluster of increased prevalence in a similar location for the two mental disorders in the northern part of Malmö. However, hierarchical geostatistical models showed that the two groups of disorders exhibited a different spatial distribution, in terms of both magnitude and spatial scale. Mental disorders due to substance consumption showed larger neighbourhood variations, and varied in space on a larger scale, than neurotic disorders. After adjustment for individual factors, the risk of substance related disorders increased with neighbourhood deprivation and neighbourhood social disorganisation. The risk of neurotic disorders only increased with contextual deprivation. Measuring contextual factors across continuous space, it was found that these associations operated on a local scale. Conclusions: Taking space into account in the analyses permitted deeper insight into the contextual determinants of mental disorders

Chemical kinetic and radiating species studies of Titan aerocapture entry

TITAN Aerocapture entry has been studied in collaboration with the Hypersonics Centre of the University Queensland (UQ), Australia The simulation of the experimental conditions and also the flight conditions are made using CFD coupled with chemistry libraries of which CHEMKIN. This can be compared to in-code implementation for the Earth reentry. Reduced models based on combustion data bases are taken for the reactions data set for Titan’s entry

Formation of Shore-Normal Grooves (Gutters) in Sandstone by Wave Action.

Regularly spaced incised shore-normal grooves (gutters) on plane consolidated surfaces in littoral and sublittoral zones are widely observed in the marine geological record. Despite their common occurrence there are few investigations into their origins in contemporary marine environments. While their formation is often attributed to wave-induced currents related to wave swash and backwash on the beach-face, no conceptual model has been advanced to explain the presence of gutters, their morphology or their quasi-regular alongshore spacing. The paper examines gutters cut in soft sandstone at Medmerry near Selsey, UK and argues that their formation is related to wave breaking and swash zone processes during an unprecedented sequence of storms in the winter of 2013/14. During this period exceptionally high near-shore waves (Hs around 6m) were recorded for the south coast beaches and these storm conditions persisted periodically through to mid-February 2014. The consequence was extensive beach erosion and the exposure of underlying substrates. In this study gutter morphology was quantified using terrestrial lidar and a wave-resolving numerical model was used to defined the nearshore wave conditions and swash characteristics. Three of the largest storm events during the winter of 2013/14 were modelled: (a) moderate waves coincident with an exceptionally high tide; (b) exceptionally high waves occurring during neap tides; and (c) high waves occurring during spring tides. The model results showed swash zone shear stress is a dome-shaped function of distance across the beach-face thereby controlling gutter depth. Further, high-speed sheet flows characterised by periodic, shore-normal, high and low speed streaks alongshore are thought to be implicated in the mechanism controlling gutter spacing. However, in any situation, the specific spacing of gutters is moderated by both the local sheet flow characteristics and the larger-scale morphological forcing. Together these factors indicate that gutter spacing is an emergent property which makes spacing unpredictable

Multilevel Modelling for Public Health and Health Services Research

This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) – a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download – not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book’s practical review of MLA comprises: Theoretical, conceptual, and methodological background Statistical background The modelling process and presentation of research Tutorials with example datasets Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis. “Leyland and Groenewegen’s wealth of teaching experience makes this book and its accompanying tutorials especially useful for a practical introduction to multilevel analysis.” ̶ Juan Merlo, Professor of Social Epidemiology, Lund University “Comprehensive and insightful. A must for anyone interested in the applications of multilevel modelling to population health”. ̶ S. (Subu) V. Subramanian, Professor of Population Health and Geography, Harvard University ; For researchers and students with a basic mastery of ordinary least squares and logistic regression Discusses multilevel analysis in context of public health, health services research, and epidemiology Includes an online component where users can download the datasets analyzed in the book, and also a freeware version of the multilevel modelling software MLwiN ​​​​​​​Can be used as part of a course on multilevel modelling, or as a self-training tex

The influence of flow discharge variations on the morphodynamics of a diffluence-confluence unit on a large river: Impacts of discharge variation on a diffluence-confluence unit

© 2017 The Authors. Earth Surface Processes and Landforms published by John Wiley & Sons Ltd. Bifurcations are key geomorphological nodes in anabranching and braided fluvial channels, controlling local bed morphology, the routing of sediment and water, and ultimately defining the stability of their associated diffluence–confluence unit. Recently, numerical modelling of bifurcations has focused on the relationship between flow conditions and the partitioning of sediment between the bifurcate channels. Herein, we report on field observations spanning September 2013 to July 2014 of the three-dimensional flow structure, bed morphological change and partitioning of both flow discharge and suspended sediment through a large diffluence–confluence unit on the Mekong River, Cambodia, across a range of flow stages (from 13 500 to 27 000 m 3 s −1 ). Analysis of discharge and sediment load throughout the diffluence–confluence unit reveals that during the highest flows (Q = 27 000 m 3 s −1 ), the downstream island complex is a net sink of sediment (losing 2600 ± 2000 kg s −1 between the diffluence and confluence), whereas during the rising limb (Q = 19 500 m 3 s −1 ) and falling limb flows (Q = 13 500 m 3 s −1 ) the sediment balance is in quasi-equilibrium. We show that the discharge asymmetry of the bifurcation varies with discharge and highlight that the influence of upstream curvature-induced water surface slope and bed morphological change may be first-order controls on bifurcation configuration. Comparison of our field data to existing bifurcation stability diagrams reveals that during lower (rising and falling limb) flow the bifurcation may be classified as unstable, yet transitions to a stable condition at high flows. However, over the long term (1959–2013) aerial imagery reveals the diffluence–confluence unit to be fairly stable. We propose, therefore, that the long-term stability of the bifurcation, as well as the larger channel planform and morphology of the diffluence–confluence unit, may be controlled by the dominant sediment transport regime of the system. © 2017 The Authors. Earth Surface Processes and Landforms published by John Wiley & Sons Ltd

How effective is the Forestry Commission Scotland's woodland improvement programme--'Woods In and Around Towns' (WIAT)--at improving psychological well-being in deprived urban communities? A quasi-experimental study

Introduction: There is a growing body of evidence that suggests that green spaces may positively influence psychological well-being. This project is designed to take advantage of a natural experiment where planned physical and social interventions to enhance access to natural environments in deprived communities provide an opportunity to prospectively assess impacts on perceived stress and mental well-being.<p></p> Study design and methods: A controlled, prospective study comprising a repeat cross-sectional survey of residents living within 1.5 km of intervention and comparison sites. Three waves of data will be collected: prephysical environment intervention (2013); postphysical environment intervention (2014) and postwoodland promotion social intervention (2015). The primary outcome will be a measure of perceived stress (Perceived Stress Scale) preintervention and postintervention. Secondary, self-report outcomes include: mental well-being (Short Warwick-Edinburgh Mental Well-being Scale), changes in physical activity (IPAQ-short form), health (EuroQoL EQ-5D), perception and use of the woodlands, connectedness to nature (Inclusion of Nature in Self Scale), social cohesion and social capital. An environmental audit will complement the study by evaluating the physical changes in the environment over time and recording any other contextual changes over time. A process evaluation will assess the implementation of the programme. A health economics analysis will assess the cost consequences of each stage of the intervention in relation to the primary and secondary outcomes of the study.<p></p> Ethics and dissemination: Ethical approval has been given by the University of Edinburgh, Edinburgh College of Art Research, Ethics and Knowledge Exchange Committee (ref. 19/06/2012). Findings will be disseminated through peer-reviewed publications, national and international conferences and, at the final stage of the project, through a workshop for those interested in implementing environmental interventions.<p></p&gt

Extreme flood-driven fluvial bank erosion and sediment loads: direct process measurements using integrated Mobile Laser Scanning (MLS) and hydro-acoustic techniques: Direct measurement of flood-driven erosion using MLS and MBES

Copyright © 2016 John Wiley & Sons, Ltd. This methods paper details the first attempt at monitoring bank erosion, flow and suspended sediment at a site during flooding on the Mekong River induced by the passage of tropical cyclones. We deployed integrated mobile laser scanning (MLS) and multibeam echo sounding (MBES), alongside acoustic Doppler current profiling (aDcp), to directly measure changes in river bank and bed at high (~0.05 m) spatial resolution, in conjunction with measurements of flow and suspended sediment dynamics. We outline the methodological steps used to collect and process this complex point cloud data, and detail the procedures used to process and calibrate the aDcp flow and sediment flux data. A comparison with conventional remote sensing methods of estimating bank erosion, using aerial images and Landsat imagery, reveals that traditional techniques are error prone at the high temporal resolutions required to quantify the patterns and volumes of bank erosion induced by the passage of individual flood events. Our analysis reveals the importance of cyclone-driven flood events in causing high rates of erosion and suspended sediment transport, with a c. twofold increase in bank erosion volumes and a fourfold increase in suspended sediment volumes in the cyclone-affected wet season. Copyright © 2016 John Wiley & Sons, Ltd

Plasma radiation for atmospheric entry at Titan: Emission spectroscopy measurements and numerical rebuilding

Emission spectroscopy measurements on a plasma representative of Titan atmosphere composition were obtained in the Inductively Coupled Plasma wind tunnel facility (VKI-Minitorch) at the von Karman Institute in Belgium. Temperatures ranged from 3600 to 5000 K, pressure was fixed at 300 mbar, and the molar composition was 1.9% CH4 and 98.1% N2. The high-pressure plasma was produced to obtain conditions close to equilibrium. In conjunction, line-by-line calculations have been carried out to assess the reliability of two distinct sets of molecular electronic transition moments, recently released, by predicting the radiative signature of high-temperature N2-CH4 plasma. The radiative transfer problem was solved by considering the plasma plume at local thermodynamic equilibrium conditions in an axisymmetric configuration. Comparisons between the synthetic and experimental spectra demonstrated good agreement for the CN Violet and high-wavelength CN Red bands, while some discrepancies were observed for the C2 Swan bands and low-wavelength CN Red band

Longitudinal thalamic white and gray matter changes associated with visual hallucinations in Parkinson’s disease

Objective: Visual hallucinations are common in Parkinson’s disease (PD) and associated with worse outcomes. Large-scale network imbalance is seen in PD-associated hallucinations, but mechanisms remain unclear. As the thalamus is critical in controlling cortical networks, structural thalamic changes could underlie network dysfunction in PD hallucinations. Methods: We used whole-brain fixel-based analysis and cortical thickness measures to examine longitudinal white and grey matter changes in 76 patients with PD (15 hallucinators, 61 non-hallucinators) and 26 controls at baseline, and after 18 months. We compared white matter and cortical thickness, adjusting for age, gender, time-between-scans and intracranial volume. To assess thalamic changes, we extracted volumes for 50 thalamic subnuclei (25 each hemisphere) and mean fibre crosssection (FC) for white matter tracts originating in each subnucleus and examined longitudinal change in PDhallucinators versus non-hallucinators. Results: PD hallucinators showed white matter changes within the corpus callosum at baseline and extensive posterior tract involvement over time. Less extensive cortical thickness changes were only seen after followup. White matter connections from the right medial mediodorsal magnocellular thalamic nucleus showed reduced FC in PD hallucinators at baseline followed by volume reductions longitudinally. After follow-up, almost all thalamic subnuclei showed tract losses in PD hallucinators compared with non-hallucinators. Interpretation: PD hallucinators show white matter loss particularly in posterior connections and in thalamic nuclei, over time with relatively preserved cortical thickness. The right medial mediodorsal thalamic nucleus shows both connectivity and volume loss in PD hallucinations. Our findings provide mechanistic insights into the drivers of network imbalance in PD hallucinations and potential therapeutic targets